Health Topical

Histadelia (Histamine High) Information -- Causes OCD/Depression Symptoms

I am posting this information on histadelia (histamine high)
in an effort to increase awareness of its existence. Many
cases of OCD and depression are misdiagnosed histadelia (root
cause), and there is very limited information and awareness
about it on the internet (a mere 13 hits on google groups and
73 on google search!).
Don't let the talk of schizophrenia scare you off -- you don't
have to be schizophrenic to be histadelic, that just
represents the extreme cases. In fact, it is believed that
Marilyn Monroe was histadelic.
The following represents information from assorted uncredited
sources. Please do not email me as the above email address is
not in use and I am not a medical professional.
--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---
Histadelia (Histamine High)
Histadelia, more common in males, is characterized by elevated
blood levels of histamine. It is estimated that 15-20% of
schizophrenics are probably histadelic. The treatment of
histadelia requires great patience because six to ten weeks
are often needed before the beginning of significant
improvement. The treatment usually takes twelve months to
complete. To find out more about this see Mental Illness: The
Nutrition Connection, a book by Carl Pfeiffer. The prognosis
is good if the histadelic patient cooperates with treatment
and works to give up detrimental addictions.
*** Signs, symptoms & indicators of Histadelia
(Histamine High):
* Allergy
* Excess mucous: Histamine can cause additional mucus
production.
* Good tolerance of cold
* Poor tolerance of heat
* Unexplained nausea
* Poor pain tolerance
* Excess/abundant saliva in mouth
* Hyperactivity: Histamine speeds up metabolism producing a
tendency towards hyperactivity.
* Frequent colds/flus
* Phobias
* Being highly motivated: Those with elevated histamine
(histadelics) tend to work compulsively.
* A hard-driving personality: Histadelics tend to work
compulsively.
* Good creativity/imagination: Histadelics are often
highly creative.
* Strong sexual desire
* Joint pain/swelling/stiffness
* Excess perspiration
* Warm skin
*** Conditions that suggest Histadelia (Histamine High):
* Allergy: Allergic Rhinitis / Hay Fever
* Depression: Histadelics are often chronically and
suicidally depressed.
* Obsessive-Compulsive Disorder (OCD): Histadelics are often
prone to obsessions, compulsions, and addictions.
* Addictions / Addictive Tendencies: Nutritional treatment
for drug and alcohol users will depend on the results of a
test for blood histamine levels. In one series of such
analysis, all users proved to have high histamine levels,
leading the scientist to conclude that this abnormality -
with its impact on brain function - is a major force in
creating addiction. [Nutrition Guide for the Prevention
and Cure of Common Ailments and Diseases, Carlton
Fredericks, PhD. p.58]
* Headaches
* Insomnia: The overarousal seen in histadelia may
contribute to insomnia.
* Muscle Pains (Myalgia)
* History of unexplained nausea
* Slender fingers / toes: Histadelics often have long
fingers and toes.
*** Recommendations for Histadelia (Histamine High):
* Methionine: Methionine supplements lower blood levels of
histamine by increasing histamine breakdown.
* Calcium
* Copper: Copper levels may be low to normal in patients
with histadelia. Copper is part of the enzyme histaminase,
which is involved in the metabolism of histamine.
* Magnesium
* Manganese
* Vitamin B6 (Pyridoxine)
* Vitamin C (Ascorbic Acid)
* Vegetarian/Vegan Diet Nutritionists recommend a low-protein,
high
complex carbohydrate diet. Histidine, which is more common
in animal
proteins, should be avoided as it can be converted into
histamine.
*** Not recommended
* Vitamin Folic Acid: Histadelics should avoid supplemental
folic acid as it can produce excess histamine. In fact,
anti-folate drugs may be required. Folic acid increases
depression in histadelic patients and a trial of folic
acid could be used to distinguish between histapenics and
histadelics. In extreme cases, folic acid in food or in
multivitamins is enough to produce the adverse effects.
*** Lab Tests
* Copper Levels: Testing serum or hair copper levels is
usually adequate for evaluating copper status when low
levels of copper are suspected and hair contamination with
copper can be ruled out. When in doubt, it would be better
to use more accurate tests such as the 24 hour urine copper
or serum ceruloplasmin.
* Histamine Levels
* Folic Acid Levels: Under certain conditions, such as
anticipated or actual pregnancy, a simple lab test for
serum folate levels is advisable. If the test results show
low levels, supplementation should be considered to prevent
potential birth defects.
* Zinc Levels
* Manganese Levels
*** Glossary
* Histamine: A chemical in the body tissues, produced by the
breakdown of histidine. It is released in allergic
reactions and causes widening of capillaries, decreased
blood pressure, increased release of gastric juice, fluid
leakage forming itchy skin and hives, and tightening of
smooth muscles of the bronchial tube and uterus.
* Metabolism: The chemical processes of living cells in which
energy is produced in order to replace and repair tissues
and maintain a healthy body. Responsible for the production
of energy, biosynthesis of important substances, and
degradation of various compounds.
--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---
Histadelia represents the chemical antithesis of histapenia in
that it involves elevated blood histamine. This condition
(involving about 20 percent of schizophrenics) is
characterized by delusions, severe depression,
obsessive/compulsive behavior, and blank-mindedness, and often
results in a diagnosis of schizo-affective disorder. Treatment
revolves around anti-folates such as calcium, methionine, and
the prescription drug Dilantin® along with augmenting
nutrients. Histadelia treatment requires great patience,
because six to ten weeks are often needed before the beginning
of significant improvement. The treatment usually takes twelve
months to complete.
--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---
Histadelic depressives have a particular imbalanced amino-acid
cycle, which results in low levels of serotonin and elevated
histamine. Histadelics often exhibit obsessive-compulsive
tendencies, perfectionism, seasonal allergies, easy tears,
high libido, and headaches. They have addictive tendencies
with a high incidence of alcoholism, drug abuse, anorexia, and
bulimia. They often are diagnosed with seasonal affective
disorder which is most serious during Fall and Winter. The
decisive chemical test for this condition is whole blood
histamine. We treat histadelia with a biochemical one-two
punch in which (1) calcium is given to release excess
histamine from tissues into the bloodstream, and (2)
methionine (SAMe) is provided to add a methy group to blood
histamine and hasten its exit from the body. With good
compliance, improvement is usually noted in 4-8 weeks with
about 3-6 months needed to correct this chemical imbalance.
--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---
Armed with the proper nutrients, I smuggled them back in to
the last hospital I was in, and took them on the sly while
mouthing my medication, and spitting it down a toilet.
After just three weeks of taking my supplements, I was doing
so much better that I was given a full medical discharge, with
the doctors scratching their heads, wondering which of their
drugs had been helping me, but none of them had been -- I was
spitting them all down the toilet where the toxic substances
belonged. That was 23 years ago.
Pfeiffer discovered that food and inhalant allergies caused me
to have an overproduction of histamine which is peripherally
stored in basophils of the blood and the tissue mast cells.
Basophil counts greater than 50 cells/cu mm and histamine
levels greater than 70 ng/ml (10 mcg%) are considered
diagnostic for histadelia. The average histamine for males was
111 mg/ml and females 107 mg/ml in a study reported in 1975.
My histamine levels were up to 126. This is significantly
different from normals: 42 and 46 mg/ml for males and females
respectively. Histadelia causes suicidal depression, paranoia,
and obsessive thinking.
The amino acid methionine (SAMe) detoxifies histamine by
methylating the ring structure forming N-methylhistamine.
Calcium, taken in the form of calcium salts reduces the
release of the bodies store of histamine. Zinc and
manganese aid the calcium-methionine program and provide
sufficient relief.
Pfeiffer also discovered that I had very high aluminum levels,
and copper levels, as well as overproduction of an enzyme
called kryptopyrolle. This enzyme robbed me of zinc, a copper
antagonist that I needed to eliminate excess copper which was
having an excitory effect on the brain as an electrolyte,
contributing to my difficulty concentrating, to thought
disorder as well as to my severe depression.
In essence: high copper levels were shorting out my brain,
interfering with neural firing. Zinc, Manganese, and vitamin C
all help to lower a copper burden. The amino acids l-tyrosine,
and l-tryptophan boost norepeniphrine and dopamine levels
respectively, also helping to alleviate depression.
--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---
Histadelia: This is a disorder, prominent in males, of too
much histamine in the blood. Estimated to affect 15-20% of
patients classified as "schizophrenic."
Symptoms include hyperactivity, compulsions, obsessions, inner
tensions, blank mind episodes, phobias, chronic depression,
and strong suicidal tendencies.
Physical signs can include little tolerance for pain, rapid
metabolism, lean build, profuse sweating, seasonal allergies,
and frequent colds.
--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---
Histadelia - In the early years of this century, at the height
of his career, Nijinski, the much-acclaimed Russian dancer,
was diagnosed as incurably insane. Nijinsky may have been
histadelic. One of the first indications of his illness
occurred when Nijinsky, who had previously been especially
caring and gentle, pushed his wife and infant child downstairs
and afterwards seemed confused about the incident. He began
refusing animal food (actually, probably a beneficial choice,
if he was histadelic), and sometimes would not eat at all for
long periods of time. He became obsessed with recurrent
visions of dead soldiers, and prone to violence, especially
when separated from the mental institute. Nijinsky never
recovered and never danced again, although his wife found that
he did not seem to have forgotten any move of any dance he
ever performed.
Histadelia is characterized by elevated blood levels of
histamine. 15-20% of schizophrenics are probably histadelic.
Histadelics tend to work compulsively and are often highly
creative. On the other hand, they are often chronically and
suicidally depressed and prey to obsessions, compulsions, and
addictions.
Typical treatment includes such nutrients as calcium,
magnesium, B6, C, zinc, manganese, and methionine (SAMe),
and limitation of intake of folic acid and histidine (common
in animal proteins). If the histadelic cooperates with
treatment and works to give up detrimental addictions, the
prognosis is good.
--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---
On the physical front, nutrient deficiencies, glucose
intolerance and allergy are extremely common in those
suffering from depression. One major cause is an excess of the
neurotransmitter hormone histamine - a condition known as
histadelia. Dr Carl Pfeiffer asks: "Do you sneeze in bright
sunlight? Cry, salivate and feel nauseous easily? Hear your
pulse in your head on the pillow at night? Have frequent
backaches, stomach and muscle cramps? Do you have regular
headaches and seasonal allergies? Have abnormal fears,
compulsions and rituals? Do you burn up food rapidly and
sometimes entertain suicidal thoughts? ...If a majority of
these apply to you, you may benefit from a low-protein, high
complex carbohydrate diet (fruits and vegetables), 500mg of
calcium, am and pm, 500mg methionine am and pm and a basic
supplement program. Avoid supplements containing folic acid as
these can raise histamine levels."
Some of our most loved stars, such as Marilyn Monroe and Judy
Garland, were likely histadelics. Drawing from over 30 years'
experience, Pfeiffer estimates that at least 20% of
schizophrenics are histadelics and these are often the problem
patients in psychiatric hospitals, since they do not respond
to the usual drug treatments, electroshock or insulin coma
'therapy'.
Blood histamine levels can be analysed and often, the
compulsive obsessions, blank mind, easy crying and confusion
may highlight an underlying chemical addiction to cane sugar,
alcohol or drugs. Histadelics experience high saliva discharge
and rarely have cavities. Often they are seen wiping saliva
from the corners of their mouth. Excess histamine presents
rapid oxidation in their body, and their high metabolic rate
and subsequent attractive body shape are sometimes potential
indicators for the underlying condition. Marilyn Monroe was
often heard to remark to photographers: "You always take
pictures of my body, but my most perfect feature is my teeth -
I have no cavities."
A high sex drive characterises the histadelic, who achieves
orgasm and sustains it easily. Drug addicts and alcoholics
also tend to be histadelic. Heroin and methadone for instance
are both powerful histamine-releasing agents. A severe
insomnia also characterises the condition, and sufferers often
use heavy doses of sedatives in order to get to sleep. The
sedatives themselves often become an addiction problem,
further compounding the plight suffered by those with
depression.
--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---
A common contributory cause of depression is an excess of
histamine, known as histadelia, which is mostly inherited.
Histamine speeds up metabolism but also causes allergic
reactions, increased mucus and saliva production and a
tendency to hyperactivity, compulsive behaviour and
depression. About 20% of those labelled schizophrenic and most
depressed people are histadelic. Some of the signs of this
tendency are insomnia, frequent headaches, body aches,
salivation and nausea.
To find out more about this consult a nutritionist or
see Mental Illness: The Nutrition Connection, a book by
Carl Pfeiffer.
Ways to overcome histadelia: Nutritionists recommend a
low-protein, high complex carbohydrate diet. That means
replacing refined carbohydrates in things like chocolate,
snacks and white bread with unrefined carbohydrates in
wholefoods and grains, fruit and vegetables, including
potatoes. Histadelics should avoid folic acid, as it can
produce excess histamine. Folic acid comes in many
multivitamin pills, and also certain vegetables such as
spinach, lettuce and broccoli. It is also found in liver
and kidneys.
--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---

^_^:
Well, thanks for that, hopefully not too many people with OCD
will now start obsessing weather or not the have Histadelia.
Lain
"Josh" <joshdallman~yahoo.com wrote in message
news:489aa4b6.0210071322.250ca106~posting.google.com...
I am posting this information on histadelia (histamine high)
in an effort to increase awareness of its existence. Many
cases of OCD and depression are misdiagnosed histadelia
(root cause), and there is very limited information and
awareness about it on the internet (a mere 13 hits on google
groups and 73 on google search!).

Don't let the talk of schizophrenia scare you off -- you
don't have to be schizophrenic to be histadelic, that just
represents the extreme cases. In fact, it is believed that
Marilyn Monroe was histadelic.

The following represents information from assorted
uncredited sources. Please do not email me as the above
email address is not in use and I am not a medical
professional.

--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---

Histadelia (Histamine High)

Histadelia, more common in males, is characterized by
elevated blood levels of histamine. It is estimated that
15-20% of schizophrenics are probably histadelic. The
treatment of histadelia requires great patience because six
to ten weeks are often needed before the beginning of
significant improvement. The treatment usually takes twelve
months to complete. To find out more about this see Mental
Illness: The Nutrition Connection, a book by Carl Pfeiffer.
The prognosis is good if the histadelic patient cooperates
with treatment and works to give up detrimental addictions.


*** Signs, symptoms & indicators of Histadelia
(Histamine High):

* Allergy

* Excess mucous: Histamine can cause additional mucus
production.

* Good tolerance of cold

* Poor tolerance of heat

* Unexplained nausea

* Poor pain tolerance

* Excess/abundant saliva in mouth

* Hyperactivity: Histamine speeds up metabolism producing
a tendency towards hyperactivity.

* Frequent colds/flus

* Phobias

* Being highly motivated: Those with elevated histamine
(histadelics) tend to work compulsively.

* A hard-driving personality: Histadelics tend to work
compulsively.

* Good creativity/imagination: Histadelics are often
highly creative.

* Strong sexual desire

* Joint pain/swelling/stiffness

* Excess perspiration

* Warm skin


*** Conditions that suggest Histadelia (Histamine High):

* Allergy: Allergic Rhinitis / Hay Fever

* Depression: Histadelics are often chronically and
suicidally depressed.

* Obsessive-Compulsive Disorder (OCD): Histadelics are
often prone to obsessions, compulsions, and addictions.

* Addictions / Addictive Tendencies: Nutritional treatment
for drug and alcohol users will depend on the results of
a test for blood histamine levels. In one series of such
analysis, all users proved to have high histamine
levels, leading the scientist to conclude that this
abnormality - with its impact on brain function - is a
major force in creating addiction. [Nutrition Guide for
the Prevention and Cure of Common Ailments and Diseases,
Carlton Fredericks, PhD. p.58]

* Headaches

* Insomnia: The overarousal seen in histadelia may
contribute to insomnia.

* Muscle Pains (Myalgia)

* History of unexplained nausea

* Slender fingers / toes: Histadelics often have long
fingers and toes.


*** Recommendations for Histadelia (Histamine High):

* Methionine: Methionine supplements lower blood levels of
histamine by increasing histamine breakdown.

* Calcium

* Copper: Copper levels may be low to normal in patients
with histadelia. Copper is part of the enzyme
histaminase, which is involved in the metabolism of
histamine.

* Magnesium

* Manganese

* Vitamin B6 (Pyridoxine)

* Vitamin C (Ascorbic Acid)

* Vegetarian/Vegan Diet Nutritionists recommend a
low-protein, high
complex carbohydrate diet. Histidine, which is more common
in animal
proteins, should be avoided as it can be converted into
histamine.


*** Not recommended

* Vitamin Folic Acid: Histadelics should avoid
supplemental folic acid as it can produce excess
histamine. In fact, anti-folate drugs may be required.
Folic acid increases depression in histadelic patients
and a trial of folic acid could be used to distinguish
between histapenics and histadelics. In extreme cases,
folic acid in food or in multivitamins is enough to
produce the adverse effects.


*** Lab Tests

* Copper Levels: Testing serum or hair copper levels is
usually adequate for evaluating copper status when low
levels of copper are suspected and hair contamination
with copper can be ruled out. When in doubt, it would be
better to use more accurate tests such as the 24 hour
urine copper or serum ceruloplasmin.

* Histamine Levels

* Folic Acid Levels: Under certain conditions, such as
anticipated or actual pregnancy, a simple lab test for
serum folate levels is advisable. If the test results
show low levels, supplementation should be considered to
prevent potential birth defects.

* Zinc Levels

* Manganese Levels


*** Glossary

* Histamine: A chemical in the body tissues, produced by
the breakdown of histidine. It is released in allergic
reactions and causes widening of capillaries, decreased
blood pressure, increased release of gastric juice, fluid
leakage forming itchy skin and hives, and tightening of
smooth muscles of the bronchial tube and uterus.

* Metabolism: The chemical processes of living cells in
which energy is produced in order to replace and repair
tissues and maintain a healthy body. Responsible for the
production of energy, biosynthesis of important
substances, and degradation of various compounds.

--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---

Histadelia represents the chemical antithesis of histapenia
in that it involves elevated blood histamine. This condition
(involving about 20 percent of schizophrenics) is
characterized by delusions, severe depression,
obsessive/compulsive behavior, and blank-mindedness, and
often results in a diagnosis of schizo-affective disorder.
Treatment revolves around anti-folates such as calcium,
methionine, and the prescription drug Dilantin® along with
augmenting nutrients. Histadelia treatment requires great
patience, because six to ten weeks are often needed before
the beginning of significant improvement. The treatment
usually takes twelve months to complete.

--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---

Histadelic depressives have a particular imbalanced
amino-acid cycle, which results in low levels of serotonin
and elevated histamine. Histadelics often exhibit
obsessive-compulsive tendencies, perfectionism, seasonal
allergies, easy tears, high libido, and headaches. They have
addictive tendencies with a high incidence of alcoholism,
drug abuse, anorexia, and bulimia. They often are diagnosed
with seasonal affective disorder which is most serious
during Fall and Winter. The decisive chemical test for this
condition is whole blood histamine. We treat histadelia with
a biochemical one-two punch in which (1) calcium is given to
release excess histamine from tissues into the bloodstream,
and (2) methionine (SAMe) is provided to add a methy group
to blood histamine and hasten its exit from the body. With
good compliance, improvement is usually noted in 4-8 weeks
with about 3-6 months needed to correct this chemical
imbalance.

--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---

Armed with the proper nutrients, I smuggled them back in to
the last hospital I was in, and took them on the sly while
mouthing my medication, and spitting it down a toilet.

After just three weeks of taking my supplements, I was doing
so much better that I was given a full medical discharge,
with the doctors scratching their heads, wondering which of
their drugs had been helping me, but none of them had been
-- I was spitting them all down the toilet where the toxic
substances belonged. That was 23 years ago.

Pfeiffer discovered that food and inhalant allergies caused
me to have an overproduction of histamine which is
peripherally stored in basophils of the blood and the tissue
mast cells. Basophil counts greater than 50 cells/cu mm and
histamine levels greater than 70 ng/ml (10 mcg%) are
considered diagnostic for histadelia. The average histamine
for males was 111 mg/ml and females 107 mg/ml in a study
reported in 1975. My histamine levels were up to 126. This
is significantly different from normals: 42 and 46 mg/ml for
males and females respectively. Histadelia causes suicidal
depression, paranoia, and obsessive thinking.

The amino acid methionine (SAMe) detoxifies histamine by
methylating the ring structure forming N-methylhistamine.
Calcium, taken in the form of calcium salts reduces the
release of the bodies store of histamine. Zinc and
manganese aid the calcium-methionine program and provide
sufficient relief.

Pfeiffer also discovered that I had very high aluminum
levels, and copper levels, as well as overproduction of an
enzyme called kryptopyrolle. This enzyme robbed me of zinc,
a copper antagonist that I needed to eliminate excess copper
which was having an excitory effect on the brain as an
electrolyte, contributing to my difficulty concentrating, to
thought disorder as well as to my severe depression.

In essence: high copper levels were shorting out my brain,
interfering with neural firing. Zinc, Manganese, and vitamin
C all help to lower a copper burden. The amino acids
l-tyrosine, and l-tryptophan boost norepeniphrine and
dopamine levels respectively, also helping to alleviate
depression.

--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---

Histadelia: This is a disorder, prominent in males, of too
much histamine in the blood. Estimated to affect 15-20% of
patients classified as "schizophrenic."

Symptoms include hyperactivity, compulsions, obsessions,
inner tensions, blank mind episodes, phobias, chronic
depression, and strong suicidal tendencies.

Physical signs can include little tolerance for pain, rapid
metabolism, lean build, profuse sweating, seasonal
allergies, and frequent colds.

--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---

Histadelia - In the early years of this century, at the
height of his career, Nijinski, the much-acclaimed Russian
dancer, was diagnosed as incurably insane. Nijinsky may have
been histadelic. One of the first indications of his illness
occurred when Nijinsky, who had previously been especially
caring and gentle, pushed his wife and infant child
downstairs and afterwards seemed confused about the
incident. He began refusing animal food (actually, probably
a beneficial choice, if he was histadelic), and sometimes
would not eat at all for long periods of time. He became
obsessed with recurrent visions of dead soldiers, and prone
to violence, especially when separated from the mental
institute. Nijinsky never recovered and never danced again,
although his wife found that he did not seem to have
forgotten any move of any dance he ever performed.

Histadelia is characterized by elevated blood levels of
histamine. 15-20% of schizophrenics are probably histadelic.
Histadelics tend to work compulsively and are often highly
creative. On the other hand, they are often chronically and
suicidally depressed and prey to obsessions, compulsions,
and addictions.

Typical treatment includes such nutrients as calcium,
magnesium, B6, C, zinc, manganese, and methionine (SAMe),
and limitation of intake of folic acid and histidine (common
in animal proteins). If the histadelic cooperates with
treatment and works to give up detrimental addictions, the
prognosis is good.

--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---

On the physical front, nutrient deficiencies, glucose
intolerance and allergy are extremely common in those
suffering from depression. One major cause is an excess of
the neurotransmitter hormone histamine - a condition known
as histadelia. Dr Carl Pfeiffer asks: "Do you sneeze in
bright sunlight? Cry, salivate and feel nauseous easily?
Hear your pulse in your head on the pillow at night? Have
frequent backaches, stomach and muscle cramps? Do you have
regular headaches and seasonal allergies? Have abnormal
fears, compulsions and rituals? Do you burn up food rapidly
and sometimes entertain suicidal thoughts? ...If a majority
of these apply to you, you may benefit from a low-protein,
high complex carbohydrate diet (fruits and vegetables),
500mg of calcium, am and pm, 500mg methionine am and pm and
a basic supplement program. Avoid supplements containing
folic acid as these can raise histamine levels."

Some of our most loved stars, such as Marilyn Monroe and
Judy Garland, were likely histadelics. Drawing from over 30
years' experience, Pfeiffer estimates that at least 20% of
schizophrenics are histadelics and these are often the
problem patients in psychiatric hospitals, since they do not
respond to the usual drug treatments, electroshock or
insulin coma 'therapy'.

Blood histamine levels can be analysed and often, the
compulsive obsessions, blank mind, easy crying and confusion
may highlight an underlying chemical addiction to cane
sugar, alcohol or drugs. Histadelics experience high saliva
discharge and rarely have cavities. Often they are seen
wiping saliva from the corners of their mouth. Excess
histamine presents rapid oxidation in their body, and their
high metabolic rate and subsequent attractive body shape are
sometimes potential indicators for the underlying condition.
Marilyn Monroe was often heard to remark to photographers:
"You always take pictures of my body, but my most perfect
feature is my teeth - I have no cavities."

A high sex drive characterises the histadelic, who achieves
orgasm and sustains it easily. Drug addicts and alcoholics
also tend to be histadelic. Heroin and methadone for
instance are both powerful histamine-releasing agents. A
severe insomnia also characterises the condition, and
sufferers often use heavy doses of sedatives in order to get
to sleep. The sedatives themselves often become an addiction
problem, further compounding the plight suffered by those
with depression.

--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---

A common contributory cause of depression is an excess of
histamine, known as histadelia, which is mostly inherited.
Histamine speeds up metabolism but also causes allergic
reactions, increased mucus and saliva production and a
tendency to hyperactivity, compulsive behaviour and
depression. About 20% of those labelled schizophrenic and
most depressed people are histadelic. Some of the signs of
this tendency are insomnia, frequent headaches, body aches,
salivation and nausea.

To find out more about this consult a nutritionist or see
Mental Illness: The Nutrition Connection, a book by Carl
Pfeiffer.

Ways to overcome histadelia: Nutritionists recommend a
low-protein, high complex carbohydrate diet. That means
replacing refined carbohydrates in things like chocolate,
snacks and white bread with unrefined carbohydrates in
wholefoods and grains, fruit and vegetables, including
potatoes. Histadelics should avoid folic acid, as it can
produce excess histamine. Folic acid comes in many
multivitamin pills, and also certain vegetables such as
spinach, lettuce and broccoli. It is also found in liver and
kidneys.

--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---

^_^:
joshdallman~yahoo.com (Josh) writes:
I am posting this information on histadelia (histamine high)
in an effort to increase awareness of its existence. [...]
Don't let the talk of schizophrenia scare you off -- you
don't have to be schizophrenic to be histadelic, that just
represents the extreme cases. [...]
Doing not too bad up to this point...
Histadelia - In the early years of this century, at the
height of his career, Nijinski, the much-acclaimed Russian
dancer, was diagnosed as incurably insane. Nijinsky may have
been histadelic. One of the first indications of his illness
occurred when Nijinsky, who had previously been especially
caring and gentle, pushed his wife and infant child
downstairs and afterwards seemed confused about the
incident. He began refusing animal food (actually, probably
a beneficial choice, if he was histadelic), and sometimes
would not eat at all for long periods of time. He became
obsessed with recurrent visions of dead soldiers, and prone
to violence, especially when separated from the mental
institute.
whereupon the obvious conclusion is that anyone prepared to
postulate an aetiology based on so little data must be living
in a fantasy world.
Visions are unusual, but all the other symptoms listed
there are absolutely standard for schizophrenia. Also,
Nijinsky's sexuality had been a confused mess for years
before his breakdown, with sexual themes playing a major
part in his subsequent delusional state - something this
theory doesn't have an explanation for, so the author just
quietly left it out.
======== Email to "jc" at this site; email to "bogus" will
======== bounce. <========
Jack Campin: 11 Third Street, Newtongrange, Midlothian EH22
4PU; 0131 6604760 http://www.purr.demon.co.uk/purrhome.html
food intolerance data and recipes, freeware logic fonts for
the Macintosh, and Scots traditional music resources

^_^:
It must be a very obscure condition indeed if a search in
PubMed gets no results. In fact a search in google did not
locate a mainstream reference to histadelia either.
"Josh" <joshdallman~yahoo.com wrote in message
news:489aa4b6.0210071322.250ca106~posting.google.com...
I am posting this information on histadelia (histamine high)
in an effort to increase awareness of its existence. Many
cases of OCD and depression are misdiagnosed histadelia
(root cause), and there is very limited information and
awareness about it on the internet (a mere 13 hits on google
groups and 73 on google search!).

Don't let the talk of schizophrenia scare you off -- you
don't have to be schizophrenic to be histadelic, that just
represents the extreme cases. In fact, it is believed that
Marilyn Monroe was histadelic.

The following represents information from assorted
uncredited sources. Please do not email me as the above
email address is not in use and I am not a medical
professional.

--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---

Histadelia (Histamine High)

Histadelia, more common in males, is characterized by
elevated blood levels of histamine. It is estimated that
15-20% of schizophrenics are probably histadelic. The
treatment of histadelia requires great patience because six
to ten weeks are often needed before the beginning of
significant improvement. The treatment usually takes twelve
months to complete. To find out more about this see Mental
Illness: The Nutrition Connection, a book by Carl Pfeiffer.
The prognosis is good if the histadelic patient cooperates
with treatment and works to give up detrimental addictions.


*** Signs, symptoms & indicators of Histadelia
(Histamine High):

* Allergy

* Excess mucous: Histamine can cause additional mucus
production.

* Good tolerance of cold

* Poor tolerance of heat

* Unexplained nausea

* Poor pain tolerance

* Excess/abundant saliva in mouth

* Hyperactivity: Histamine speeds up metabolism producing
a tendency towards hyperactivity.

* Frequent colds/flus

* Phobias

* Being highly motivated: Those with elevated histamine
(histadelics) tend to work compulsively.

* A hard-driving personality: Histadelics tend to work
compulsively.

* Good creativity/imagination: Histadelics are often
highly creative.

* Strong sexual desire

* Joint pain/swelling/stiffness

* Excess perspiration

* Warm skin


*** Conditions that suggest Histadelia (Histamine High):

* Allergy: Allergic Rhinitis / Hay Fever

* Depression: Histadelics are often chronically and
suicidally depressed.

* Obsessive-Compulsive Disorder (OCD): Histadelics are
often prone to obsessions, compulsions, and addictions.

* Addictions / Addictive Tendencies: Nutritional treatment
for drug and alcohol users will depend on the results of
a test for blood histamine levels. In one series of such
analysis, all users proved to have high histamine
levels, leading the scientist to conclude that this
abnormality - with its impact on brain function - is a
major force in creating addiction. [Nutrition Guide for
the Prevention and Cure of Common Ailments and Diseases,
Carlton Fredericks, PhD. p.58]

* Headaches

* Insomnia: The overarousal seen in histadelia may
contribute to insomnia.

* Muscle Pains (Myalgia)

* History of unexplained nausea

* Slender fingers / toes: Histadelics often have long
fingers and toes.


*** Recommendations for Histadelia (Histamine High):

* Methionine: Methionine supplements lower blood levels of
histamine by increasing histamine breakdown.

* Calcium

* Copper: Copper levels may be low to normal in patients
with histadelia. Copper is part of the enzyme
histaminase, which is involved in the metabolism of
histamine.

* Magnesium

* Manganese

* Vitamin B6 (Pyridoxine)

* Vitamin C (Ascorbic Acid)

* Vegetarian/Vegan Diet Nutritionists recommend a
low-protein, high
complex carbohydrate diet. Histidine, which is more common
in animal
proteins, should be avoided as it can be converted into
histamine.


*** Not recommended

* Vitamin Folic Acid: Histadelics should avoid
supplemental folic acid as it can produce excess
histamine. In fact, anti-folate drugs may be required.
Folic acid increases depression in histadelic patients
and a trial of folic acid could be used to distinguish
between histapenics and histadelics. In extreme cases,
folic acid in food or in multivitamins is enough to
produce the adverse effects.


*** Lab Tests

* Copper Levels: Testing serum or hair copper levels is
usually adequate for evaluating copper status when low
levels of copper are suspected and hair contamination
with copper can be ruled out. When in doubt, it would be
better to use more accurate tests such as the 24 hour
urine copper or serum ceruloplasmin.

* Histamine Levels

* Folic Acid Levels: Under certain conditions, such as
anticipated or actual pregnancy, a simple lab test for
serum folate levels is advisable. If the test results
show low levels, supplementation should be considered to
prevent potential birth defects.

* Zinc Levels

* Manganese Levels


*** Glossary

* Histamine: A chemical in the body tissues, produced by
the breakdown of histidine. It is released in allergic
reactions and causes widening of capillaries, decreased
blood pressure, increased release of gastric juice, fluid
leakage forming itchy skin and hives, and tightening of
smooth muscles of the bronchial tube and uterus.

* Metabolism: The chemical processes of living cells in
which energy is produced in order to replace and repair
tissues and maintain a healthy body. Responsible for the
production of energy, biosynthesis of important
substances, and degradation of various compounds.

--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---

Histadelia represents the chemical antithesis of histapenia
in that it involves elevated blood histamine. This condition
(involving about 20 percent of schizophrenics) is
characterized by delusions, severe depression,
obsessive/compulsive behavior, and blank-mindedness, and
often results in a diagnosis of schizo-affective disorder.
Treatment revolves around anti-folates such as calcium,
methionine, and the prescription drug Dilantin® along with
augmenting nutrients. Histadelia treatment requires great
patience, because six to ten weeks are often needed before
the beginning of significant improvement. The treatment
usually takes twelve months to complete.

--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---

Histadelic depressives have a particular imbalanced
amino-acid cycle, which results in low levels of serotonin
and elevated histamine. Histadelics often exhibit
obsessive-compulsive tendencies, perfectionism, seasonal
allergies, easy tears, high libido, and headaches. They have
addictive tendencies with a high incidence of alcoholism,
drug abuse, anorexia, and bulimia. They often are diagnosed
with seasonal affective disorder which is most serious
during Fall and Winter. The decisive chemical test for this
condition is whole blood histamine. We treat histadelia with
a biochemical one-two punch in which (1) calcium is given to
release excess histamine from tissues into the bloodstream,
and (2) methionine (SAMe) is provided to add a methy group
to blood histamine and hasten its exit from the body. With
good compliance, improvement is usually noted in 4-8 weeks
with about 3-6 months needed to correct this chemical
imbalance.

--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---

Armed with the proper nutrients, I smuggled them back in to
the last hospital I was in, and took them on the sly while
mouthing my medication, and spitting it down a toilet.

After just three weeks of taking my supplements, I was doing
so much better that I was given a full medical discharge,
with the doctors scratching their heads, wondering which of
their drugs had been helping me, but none of them had been
-- I was spitting them all down the toilet where the toxic
substances belonged. That was 23 years ago.

Pfeiffer discovered that food and inhalant allergies caused
me to have an overproduction of histamine which is
peripherally stored in basophils of the blood and the tissue
mast cells. Basophil counts greater than 50 cells/cu mm and
histamine levels greater than 70 ng/ml (10 mcg%) are
considered diagnostic for histadelia. The average histamine
for males was 111 mg/ml and females 107 mg/ml in a study
reported in 1975. My histamine levels were up to 126. This
is significantly different from normals: 42 and 46 mg/ml for
males and females respectively. Histadelia causes suicidal
depression, paranoia, and obsessive thinking.

The amino acid methionine (SAMe) detoxifies histamine by
methylating the ring structure forming N-methylhistamine.
Calcium, taken in the form of calcium salts reduces the
release of the bodies store of histamine. Zinc and
manganese aid the calcium-methionine program and provide
sufficient relief.

Pfeiffer also discovered that I had very high aluminum
levels, and copper levels, as well as overproduction of an
enzyme called kryptopyrolle. This enzyme robbed me of zinc,
a copper antagonist that I needed to eliminate excess copper
which was having an excitory effect on the brain as an
electrolyte, contributing to my difficulty concentrating, to
thought disorder as well as to my severe depression.

In essence: high copper levels were shorting out my brain,
interfering with neural firing. Zinc, Manganese, and vitamin
C all help to lower a copper burden. The amino acids
l-tyrosine, and l-tryptophan boost norepeniphrine and
dopamine levels respectively, also helping to alleviate
depression.

--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---

Histadelia: This is a disorder, prominent in males, of too
much histamine in the blood. Estimated to affect 15-20% of
patients classified as "schizophrenic."

Symptoms include hyperactivity, compulsions, obsessions,
inner tensions, blank mind episodes, phobias, chronic
depression, and strong suicidal tendencies.

Physical signs can include little tolerance for pain, rapid
metabolism, lean build, profuse sweating, seasonal
allergies, and frequent colds.

--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---

Histadelia - In the early years of this century, at the
height of his career, Nijinski, the much-acclaimed Russian
dancer, was diagnosed as incurably insane. Nijinsky may have
been histadelic. One of the first indications of his illness
occurred when Nijinsky, who had previously been especially
caring and gentle, pushed his wife and infant child
downstairs and afterwards seemed confused about the
incident. He began refusing animal food (actually, probably
a beneficial choice, if he was histadelic), and sometimes
would not eat at all for long periods of time. He became
obsessed with recurrent visions of dead soldiers, and prone
to violence, especially when separated from the mental
institute. Nijinsky never recovered and never danced again,
although his wife found that he did not seem to have
forgotten any move of any dance he ever performed.

Histadelia is characterized by elevated blood levels of
histamine. 15-20% of schizophrenics are probably histadelic.
Histadelics tend to work compulsively and are often highly
creative. On the other hand, they are often chronically and
suicidally depressed and prey to obsessions, compulsions,
and addictions.

Typical treatment includes such nutrients as calcium,
magnesium, B6, C, zinc, manganese, and methionine (SAMe),
and limitation of intake of folic acid and histidine (common
in animal proteins). If the histadelic cooperates with
treatment and works to give up detrimental addictions, the
prognosis is good.

--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---

On the physical front, nutrient deficiencies, glucose
intolerance and allergy are extremely common in those
suffering from depression. One major cause is an excess of
the neurotransmitter hormone histamine - a condition known
as histadelia. Dr Carl Pfeiffer asks: "Do you sneeze in
bright sunlight? Cry, salivate and feel nauseous easily?
Hear your pulse in your head on the pillow at night? Have
frequent backaches, stomach and muscle cramps? Do you have
regular headaches and seasonal allergies? Have abnormal
fears, compulsions and rituals? Do you burn up food rapidly
and sometimes entertain suicidal thoughts? ...If a majority
of these apply to you, you may benefit from a low-protein,
high complex carbohydrate diet (fruits and vegetables),
500mg of calcium, am and pm, 500mg methionine am and pm and
a basic supplement program. Avoid supplements containing
folic acid as these can raise histamine levels."

Some of our most loved stars, such as Marilyn Monroe and
Judy Garland, were likely histadelics. Drawing from over 30
years' experience, Pfeiffer estimates that at least 20% of
schizophrenics are histadelics and these are often the
problem patients in psychiatric hospitals, since they do not
respond to the usual drug treatments, electroshock or
insulin coma 'therapy'.

Blood histamine levels can be analysed and often, the
compulsive obsessions, blank mind, easy crying and confusion
may highlight an underlying chemical addiction to cane
sugar, alcohol or drugs. Histadelics experience high saliva
discharge and rarely have cavities. Often they are seen
wiping saliva from the corners of their mouth. Excess
histamine presents rapid oxidation in their body, and their
high metabolic rate and subsequent attractive body shape are
sometimes potential indicators for the underlying condition.
Marilyn Monroe was often heard to remark to photographers:
"You always take pictures of my body, but my most perfect
feature is my teeth - I have no cavities."

A high sex drive characterises the histadelic, who achieves
orgasm and sustains it easily. Drug addicts and alcoholics
also tend to be histadelic. Heroin and methadone for
instance are both powerful histamine-releasing agents. A
severe insomnia also characterises the condition, and
sufferers often use heavy doses of sedatives in order to get
to sleep. The sedatives themselves often become an addiction
problem, further compounding the plight suffered by those
with depression.

--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---

A common contributory cause of depression is an excess of
histamine, known as histadelia, which is mostly inherited.
Histamine speeds up metabolism but also causes allergic
reactions, increased mucus and saliva production and a
tendency to hyperactivity, compulsive behaviour and
depression. About 20% of those labelled schizophrenic and
most depressed people are histadelic. Some of the signs of
this tendency are insomnia, frequent headaches, body aches,
salivation and nausea.

To find out more about this consult a nutritionist or see
Mental Illness: The Nutrition Connection, a book by Carl
Pfeiffer.

Ways to overcome histadelia: Nutritionists recommend a
low-protein, high complex carbohydrate diet. That means
replacing refined carbohydrates in things like chocolate,
snacks and white bread with unrefined carbohydrates in
wholefoods and grains, fruit and vegetables, including
potatoes. Histadelics should avoid folic acid, as it can
produce excess histamine. Folic acid comes in many
multivitamin pills, and also certain vegetables such as
spinach, lettuce and broccoli. It is also found in liver and
kidneys.

--- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- ---

^_^:
However I stopped eating bananas because of allergies and I
feel better for it (bananas are high in histamines).
"Mad McFarqhuar" <antispam~address..com wrote in message
news:3df0a1a3$0$2731$afc38c87~news.optusnet.com.au...
It must be a very obscure condition indeed if a search in
PubMed gets no results. In fact a search in google did not
locate a mainstream reference
to
histadelia either.



"Josh" <joshdallman~yahoo.com wrote in message
news:489aa4b6.0210071322.250ca106~posting.google.com...
I am posting this information on histadelia (histamine
high) in an effort to increase awareness of its existence.
Many cases of OCD and depression are misdiagnosed
histadelia (root cause), and there is very limited
information and awareness about it on the internet (a mere
13 hits on google groups and 73 on google search!).

Don't let the talk of schizophrenia scare you off -- you
don't have to be schizophrenic to be histadelic, that just
represents the extreme cases. In fact, it is believed that
Marilyn Monroe was histadelic.

The following represents information from assorted
uncredited sources. Please do not email me as the above
email address is not in use and I am not a medical
professional.

--- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- --- ---

Histadelia (Histamine High)

Histadelia, more common in males, is characterized by
elevated blood levels of histamine. It is estimated that
15-20% of schizophrenics are probably histadelic. The
treatment of histadelia requires great patience because
six to ten weeks are often needed before the beginning of
significant improvement. The treatment usually takes
twelve months to complete. To find out more about this see
Mental Illness: The Nutrition Connection, a book by Carl
Pfeiffer. The prognosis is good if the histadelic patient
cooperates with treatment and works to give up detrimental
addictions.


*** Signs, symptoms & indicators of Histadelia (Histamine
High):

* Allergy

* Excess mucous: Histamine can cause additional mucus
production.

* Good tolerance of cold

* Poor tolerance of heat

* Unexplained nausea

* Poor pain tolerance

* Excess/abundant saliva in mouth

* Hyperactivity: Histamine speeds up metabolism
producing a tendency towards hyperactivity.

* Frequent colds/flus

* Phobias

* Being highly motivated: Those with elevated histamine
(histadelics) tend to work compulsively.

* A hard-driving personality: Histadelics tend to work
compulsively.

* Good creativity/imagination: Histadelics are often
highly creative.

* Strong sexual desire

* Joint pain/swelling/stiffness

* Excess perspiration

* Warm skin


*** Conditions that suggest Histadelia (Histamine High):

* Allergy: Allergic Rhinitis / Hay Fever

* Depression: Histadelics are often chronically and
suicidally depressed.

* Obsessive-Compulsive Disorder (OCD): Histadelics are
often prone to obsessions, compulsions, and
addictions.

* Addictions / Addictive Tendencies: Nutritional
treatment for drug and alcohol users will depend on
the results of a test for blood histamine levels. In
one series of such analysis, all users proved to have
high histamine levels, leading the scientist to
conclude that this abnormality - with its impact on
brain function - is a major force in creating
addiction. [Nutrition Guide for the Prevention and
Cure of Common Ailments and Diseases, Carlton
Fredericks, PhD. p.58]

* Headaches

* Insomnia: The overarousal seen in histadelia may
contribute to insomnia.

* Muscle Pains (Myalgia)

* History of unexplained nausea

* Slender fingers / toes: Histadelics often have long
fingers and toes.


*** Recommendations for Histadelia (Histamine High):

* Methionine: Methionine supplements lower blood levels
of histamine by increasing histamine breakdown.

* Calcium

* Copper: Copper levels may be low to normal in patients
with histadelia. Copper is part of the enzyme
histaminase, which is involved in the metabolism of
histamine.

* Magnesium

* Manganese

* Vitamin B6 (Pyridoxine)

* Vitamin C (Ascorbic Acid)

* Vegetarian/Vegan Diet Nutritionists recommend a
low-protein, high
complex carbohydrate diet. Histidine, which is more
common in animal
proteins, should be avoided as it can be converted into
histamine.


*** Not recommended

* Vitamin Folic Acid: Histadelics should avoid
supplemental folic acid as it can produce excess
histamine. In fact, anti-folate drugs may be required.
Folic acid increases depression in histadelic patients
and a trial of folic acid could be used to distinguish
between histapenics and histadelics. In extreme cases,
folic acid in food or in multivitamins is enough to
produce the adverse effects.


*** Lab Tests

* Copper Levels: Testing serum or hair copper levels is
usually adequate for evaluating copper status when low
levels of copper are suspected and hair contamination
with copper can be ruled out. When in doubt, it would
be better to use more accurate tests such as the 24
hour urine copper or serum ceruloplasmin.

* Histamine Levels

* Folic Acid Levels: Under certain conditions, such as
anticipated or actual pregnancy, a simple lab test for
serum folate levels is advisable. If the test results
show low levels, supplementation should be considered
to prevent potential birth defects.

* Zinc Levels

* Manganese Levels


*** Glossary

* Histamine: A chemical in the body tissues, produced by
the breakdown of histidine. It is released in allergic
reactions and causes widening of capillaries, decreased
blood pressure, increased release of gastric juice,
fluid leakage forming itchy skin and hives, and
tightening of smooth muscles of the bronchial tube and
uterus.

* Metabolism: The chemical processes of living cells in
which energy is produced in order to replace and repair
tissues and maintain a healthy body. Responsible for
the production of energy, biosynthesis of important
substances, and degradation of various compounds.

--- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- --- ---

Histadelia represents the chemical antithesis of
histapenia in that it involves elevated blood histamine.
This condition (involving about 20 percent of
schizophrenics) is characterized by delusions, severe
depression, obsessive/compulsive behavior, and
blank-mindedness, and often results in a diagnosis of
schizo-affective disorder. Treatment revolves around
anti-folates such as calcium, methionine, and the
prescription drug Dilantin® along with augmenting
nutrients. Histadelia treatment requires great patience,
because six to ten weeks are often needed before the
beginning of significant improvement. The treatment
usually takes twelve months to complete.

--- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- --- ---

Histadelic depressives have a particular imbalanced
amino-acid cycle, which results in low levels of serotonin
and elevated histamine. Histadelics often exhibit
obsessive-compulsive tendencies, perfectionism, seasonal
allergies, easy tears, high libido, and headaches. They
have addictive tendencies with a high incidence of
alcoholism, drug abuse, anorexia, and bulimia. They often
are diagnosed with seasonal affective disorder which is
most serious during Fall and Winter. The decisive chemical
test for this condition is whole blood histamine. We treat
histadelia with a biochemical one-two punch in which (1)
calcium is given to release excess histamine from tissues
into the bloodstream, and (2) methionine (SAMe) is
provided to add a methy group to blood histamine and
hasten its exit from the body. With good compliance,
improvement is usually noted in 4-8 weeks with about 3-6
months needed to correct this chemical imbalance.

--- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- --- ---

Armed with the proper nutrients, I smuggled them back in
to the last hospital I was in, and took them on the sly
while mouthing my medication, and spitting it down a
toilet.

After just three weeks of taking my supplements, I was
doing so much better that I was given a full medical
discharge, with the doctors scratching their heads,
wondering which of their drugs had been helping me, but
none of them had been -- I was spitting them all down the
toilet where the toxic substances belonged. That was 23
years ago.

Pfeiffer discovered that food and inhalant allergies
caused me to have an overproduction of histamine which is
peripherally stored in basophils of the blood and the
tissue mast cells. Basophil counts greater than 50
cells/cu mm and histamine levels greater than 70 ng/ml (10
mcg%) are considered diagnostic for histadelia. The
average histamine for males was 111 mg/ml and females 107
mg/ml in a study reported in 1975. My histamine levels
were up to 126. This is significantly different from
normals: 42 and 46 mg/ml for males and females
respectively. Histadelia causes suicidal depression,
paranoia, and obsessive thinking.

The amino acid methionine (SAMe) detoxifies histamine by
methylating the ring structure forming N-methylhistamine.
Calcium, taken in the form of calcium salts reduces the
release of the bodies store of histamine. Zinc and
manganese aid the calcium-methionine program and provide
sufficient relief.

Pfeiffer also discovered that I had very high aluminum
levels, and copper levels, as well as overproduction of an
enzyme called kryptopyrolle. This enzyme robbed me of
zinc, a copper antagonist that I needed to eliminate
excess copper which was having an excitory effect on the
brain as an electrolyte, contributing to my difficulty
concentrating, to thought disorder as well as to my severe
depression.

In essence: high copper levels were shorting out my brain,
interfering with neural firing. Zinc, Manganese, and
vitamin C all help to lower a copper burden. The amino
acids l-tyrosine, and l-tryptophan boost norepeniphrine
and dopamine levels respectively, also helping to
alleviate depression.

--- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- --- ---

Histadelia: This is a disorder, prominent in males, of too
much histamine in the blood. Estimated to affect 15-20% of
patients classified as "schizophrenic."

Symptoms include hyperactivity, compulsions, obsessions,
inner tensions, blank mind episodes, phobias, chronic
depression, and strong suicidal tendencies.

Physical signs can include little tolerance for pain,
rapid metabolism, lean build, profuse sweating, seasonal
allergies, and frequent colds.

--- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- --- ---

Histadelia - In the early years of this century, at the
height of his career, Nijinski, the much-acclaimed Russian
dancer, was diagnosed as incurably insane. Nijinsky may
have been histadelic. One of the first indications of his
illness occurred when Nijinsky, who had previously been
especially caring and gentle, pushed his wife and infant
child downstairs and afterwards seemed confused about the
incident. He began refusing animal food (actually,
probably a beneficial choice, if he was histadelic), and
sometimes would not eat at all for long periods of time.
He became obsessed with recurrent visions of dead
soldiers, and prone to violence, especially when separated
from the mental institute. Nijinsky never recovered and
never danced again, although his wife found that he did
not seem to have forgotten any move of any dance he ever
performed.

Histadelia is characterized by elevated blood levels of
histamine. 15-20% of schizophrenics are probably
histadelic. Histadelics tend to work compulsively and are
often highly creative. On the other hand, they are often
chronically and suicidally depressed and prey to
obsessions, compulsions, and addictions.

Typical treatment includes such nutrients as calcium,
magnesium, B6, C, zinc, manganese, and methionine (SAMe),
and limitation of intake of folic acid and histidine
(common in animal proteins). If the histadelic cooperates
with treatment and works to give up detrimental
addictions, the prognosis is good.

--- --- --- --- --- --- --- --- --- --- --- --- --- ---
--- --- --- --- --- ---

On the physical front, nutrient deficiencies, glucose
intolerance and allergy are extremely common in those
suffering from depression. One major cause is an excess of
the neurotransmitter hormone histamine - a condition known
as histadelia. Dr Carl Pfeiffer asks: "Do you sneeze in
bright sunlight? Cry, salivate and feel nauseous easily?
Hear your pulse in your head on the pillow at night? Have
frequent backaches, stomach and muscle cramps? Do you have
regular headaches and seasonal allergies? Have abnormal
fears, compulsions and rituals? Do you burn up food
rapidly and sometimes entertain suicidal thoughts? ...If a
majority of these apply to you, you may benefit from a
low-protein, high complex carbohydrate diet (fruits and
vegetables), 500mg of calcium, am and pm, 500mg methionine
am and pm and a basic supplement program. Avoid
supplements containing folic acid as these can raise
histamine levels."

Some of our most loved stars, such as Marilyn Monroe and
Judy Garland, were likely histadelics. Drawing from over
30 years' experience, Pfeiffer estimates that at least 20%
of schizophrenics are histadelics and these are often the
problem patients in psychiatric hospitals, since they do
not respond to the usual drug treatments, electroshock or
insulin coma 'therapy'.

Blood histamine levels can be analysed and often, the
compulsive obsessions, blank mind, easy crying and
confusion may highlight an underlying chemical addiction
to cane sugar, alcohol or drugs. Histadelics experience
high saliva discharge and rarely have cavities. Often they
are seen wiping saliva from the corners of their mouth.
Excess histamine presents rapid oxidation in their body,
and their high metabolic rate and subsequent attractive
body shape are sometimes potential indicators for the
underlying condition. Marilyn Monroe was often heard to
remark to photographers: "You always take pictures of my
body, but my most perfect feature is my teeth - I have no
cavities."

A high sex drive characterises the histadelic, who
achieves orgasm and sustains it easily. Drug addicts and
alcoholics also tend to be histadelic. Heroin and
methadone for instance are both powerful
histamine-releasing agents. A severe insomnia also
characterises the condition, and sufferers often use heavy
doses of sedatives in order to get to sleep. The sedatives
themselves often become an addiction problem, further
compounding the plight suffered by those with depression.

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A common contributory cause of depression is an excess of
histamine, known as histadelia, which is mostly inherited.
Histamine speeds up metabolism but also causes allergic
reactions, increased mucus and saliva production and a
tendency to hyperactivity, compulsive behaviour and
depression. About 20% of those labelled schizophrenic and
most depressed people are histadelic. Some of the signs of
this tendency are insomnia, frequent headaches, body
aches, salivation and nausea.

To find out more about this consult a nutritionist or see
Mental Illness: The Nutrition Connection, a book by Carl
Pfeiffer.

Ways to overcome histadelia: Nutritionists recommend a
low-protein, high complex carbohydrate diet. That means
replacing refined carbohydrates in things like chocolate,
snacks and white bread with unrefined carbohydrates in
wholefoods and grains, fruit and vegetables, including
potatoes. Histadelics should avoid folic acid, as it can
produce excess histamine. Folic acid comes in many
multivitamin pills, and also certain vegetables such as
spinach, lettuce and broccoli. It is also found in liver
and kidneys.

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