NCB first seized 221 kg of amphetamine from two persons at Miyapur area in Hyderabad on September 30.
Venkat Rama Rao, a research scientist in a reputed private chemical firm of Bengaluru, had come to Hyderabad to collect the contraband from Ravi Shankar Rao, NCB said.
After Venkat and Ravi Shankar were arrested, 30 grams of amphetamine and Rs. 1.23 crore in cash were seized from a house rented by Venkat near Electronic City in Bengaluru, and his wife was also arrested.
Further, 10 kg of amphetamine was seized from a manufacturing lab in Bollaurm area here on October 1.
More members of this network were under the scanner.
The seized amphetamine was worth about Rs. 45 crore, NCB added.