The drug user is seen being lifted from the floor outside a shop in Lexington, Kentucky, by two cops.
He then begins attacking the officers, flailing around and growling like a scene from hit TV show The Walking Dead.
The two officers fire their Tazers at the crazed man, who smashes his head into a window, shattering it, before falling to the floor.
He continues to attack from the floor as officers yell “stay down” and is eventually subdued.
Cops told WHAS11 the man was overdosing on the synthetic drug which is similar to drugs like cannabis substitutes Spice and Black Mamba, which are causing chaos across the UK.